Synthesis and cytotoxicity studies of 1-propenyl-1,3-dihydro-benzimidazol-2-one
نویسندگان
چکیده
منابع مشابه
1-Benzyl-1H-benzimidazol-2(3H)-one
The fused five- and six-membered rings in the title compound, C(14)H(12)N(2)O, are essentially planar, the largest deviation from the mean plane being 0.023 (2) Å. The dihedral angle between the benzimidazole mean plane and the phenyl ring is 68.50 (6)°. In the crystal, each mol-ecule is linked to its symmetry equivalent created by a crystallographic inversion center by pairs of N-H⋯O hydrogen ...
متن کامل1-Nonyl-1H-benzimidazol-2(3H)-one
The crystal structure of the title compound, C(16)H(24)N(2)O, is built up from two fused six- and five-membered rings linked to C(9)H(19) chains. The fused-ring system is essentially planar, the largest deviation from the mean plane being 0.009 (2) Å. The chain is nearly perpendicular to this plane [dihedral angle = 80.27 (17)°]. In the crystal, inter-molecular N-H⋯O hydrogen bonds form dimers ...
متن کامل1-Octyl-1H-benzimidazol-2(3H)-one
In the title compound, C(15)H(22)N(2)O, the octyl group adopts an all-trans conformation. In the crystal, mol-ecules form centrosymmetric dimers with an R(2) (2)(8) graph-set motif, linked by pairs of N-H⋯O hydrogen bonds. In addition, C-H⋯O contacts are observed.
متن کامل1-(Prop-2-ynyl)-1H-benzimidazol-2(3H)-one
The benzimidazolone part of the title mol-ecule, C10H8N2O, is almost planar [r.m.s. deviation = 0.014 (1) Å] and the NCH2C CH group forms a dihedral angle of 67.95 (6)° with its best plane. In the crystal, mol-ecules form inversion dimers via pairs of N-H⋯O hydrogen bonds. C-H⋯O inter-actions connect the dimers, forming a two-dimensional polymeric network parallel to (100).
متن کامل1-Decyl-6-nitro-1H-benzimidazol-2(3H)-one
The title mol-ecule, C(17)H(25)N(3)O(3), is built up from fused six- and five-membered rings linked to a -C(10)H(21) chain. The fused-ring system is essentially planar, the largest deviation from the mean plane being 0.009 (2) Å. The chain is roughly perpendic-ular to this plane, making a dihedral angle of 79.5 (2)°. In the crystal, N-H⋯O hydrogen bonds build infinite chains along [010]. There ...
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ژورنال
عنوان ژورنال: Journal of Chemical Biology
سال: 2015
ISSN: 1864-6158,1864-6166
DOI: 10.1007/s12154-015-0130-8